Delprof is an excellent program to delete your users’ profiles:
By the way, if you want to do all this manually, here is the procedure for that:
Additionally, you may want to delete the roaming profiles on your central file server. It is usually difficult to to that because the files are in use. I use a nice little utility called unlocker for that.
I run this FOR loop on a command line on the server hosting the roaming profiles:
cd C:\Program Files\Unlocker
FOR /D %G in (“E:\Shares\Remote Desktop Services\Profile\*”) DO (unlocker “%G” /D /S & timeout /t 30 /nobreak)
Note that if you have a lot of profiles, it will take a long time!