Delprof is an excellent program to delete your users’ profiles: http://helgeklein.com/free-tools/delprof2-user-profile-deletion-tool/ By the way, if you want to do all this manually, here is the procedure for that: http://community.spiceworks.com/how_to/show/1595-how-to-delete-a-user-profile-from-server-2008-terminal-server Additionally, you may want to delete the roaming profiles on your central file server. It is usually difficult to to that because the files are in use. I use a nice little utility called unlocker for that. I run this FOR loop on a command line on the server hosting the roaming profiles: cd C:\Program Files\UnlockerFOR /D %G in (“E:\Shares\Remote Desktop Services\Profile\*”) DO (unlocker “%G” /D /S & timeout /t 30 /nobreak) Note that if you have a lot of profiles,…